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Meta-Analysis and Clinical Guidance of Oxygenated Hypothermic Machine Perfusion for Kidney Transplantation
In the first meta-analysis examining the role of HMPO2 in kidney transplantation finds it may lower adverse events, particularly in DCD cases.
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World Transplant Congress (WTC) 2025 – San Francisco
Event date: August 2-5, 2025
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Waters Medical Systems DCX FDA-cleared
The future of kidney perfusion just got FDA–cleared.
Meta-Analysis and Clinical Guidance of Oxygenated Hypothermic Machine Perfusion for Kidney Transplantation
Machine PerfusionIn the first meta-analysis examining the role of HMPO2 in kidney transplantation finds it may lower adverse events, particularly in DCD cases.
Delayed Kidney Transplantation After 83 Hours of Cold Ischemia Time In Combined Liver-Kidney Transplant
Machine PerfusionThe field of kidney transplantation (KTx) has evolved with hypothermic machine perfusion (HMP) to extend the time between procurement and transplant expanding the shipping distance (e.g. East-to-West coast in the U.S.). HMP also enabled to limit the harmful effect of cold ischemia time (CIT), therefore, decreased the rate of delayed graft function (DGF).
Benefits of active oxygenation during hypothermic machine perfusion of kidneys in a preclinical model of deceased after cardiac death donors
Machine PerfusionDeceased after cardiac death donors (DCDs) represent a valuable source of organs; however, preventing poor outcome is difficult, even with the use of machine perfusion (MP).
Hypothermic Machine Perfusion Preservation of the DCD Kidney: Machine Effects
Machine PerfusionKidneys from DCD donors represent a significant pool, but preservation problems exist.The study objective was to test the importance of machine type for hypothermic preservation of DCD kidneys.
Machine perfusion following static cold storage preservation in kidney transplantation
Machine PerfusionDonor-matched pairanalysis of the prognostic impact of longer pump time.
Favorable Outcomes With Machine Perfusion and Longer Pump Times in Kidney Transplantation
Machine PerfusionA major issue in optimizing kidney transplant outcome has been how to best preserve deceased donor (DD) kidneys after retrieval for transplantation.
Current State of Hypothermic Machine Perfusion Preservation of Organs: The Clinical Perspective
Machine PerfusionFocusing on the application of hypothermic perfusion technology as a topic of current interest with the potential to improve the quantity and quality of donor organs and the outcome of transplantation.
Preservation Methods for Kidney and Liver
Machine PerfusionCurrently in the U.S. there are over 100,000 patients awaiting kidney or liver transplants with transplant rates of only 20% for kidney and 38% for liver.
Influence of Pulsatile Perfusion Preservation on Outcomes in Kidney Transplantation from Expanded Criteria Donors
Machine PerfusionExpanded criteria donors (ECDs) increase the donor organ pool, but the value of transplanting these kidneys has been questioned because of concerns about diminished survival, poorer renal function, and higher rates of delayed graft function.