
New chances matter
Waters Medical Systems empowers transplant teams to improve transplant success and graft survival rates—enhancing patients’ lives.
Explore our technologies
RM4®
Hypothermic oxygenated machine perfusion of either one or two kidneys.

Waters IGL® Pulsatile Perfusion Solution (PPS)
Solution for machine perfusion of kidneys

Waters IGL® Cold Storage Solution
Cold storage solution for kidney, liver, and pancreas

Celsior®
Cold storage solution for heart
IGL-App
Increased clinical control and oversight at your fingertips.
The IGL app provides remote monitoring of RM4Ⓡ organ perfusion data—flow rate, pressure, temperature, and time. With a secure cloud-connected interface, it enables healthcare teams to track critical parameters from anywhere, improving coordination. This app ensures fast, continuous oversight, promoting quality care and extending expert support during crucial moments.
Overview
The gold standard in kidney preservation technology
RM4Ⓡ combines pulsatile hypothermic machine perfusion and active oxygenation to optimize donor kidney viability for 24 hours.
Clinical research
Read the clinical research that informs our technology.
Long-Term Outcome of Myocardial Protection in Heart Transplantation: Comparison Among 3 Different Solutions
Preservation SolutionsA new single-center, 20-year retrospective study of 528 analyzed adult heart transplants compared outcomes across three cardioplegic solutions: Celsior, HTK-Custodiol, and St Thomas.
Effect of cold storage solution on warm ischemia-induced myocardial plasma membrane damage and pyroptosis in human hearts from circulatory death donors
Preservation SolutionsComparison of the effects of Celsior Solution (CS) cold preservation with normal saline (NS) on myocardial membrane disruption and pyroptosis in human DCD hearts, with varying warm ischemia times (WIT) and cold storage durations.
Meta-Analysis and Clinical Guidance of Oxygenated Hypothermic Machine Perfusion for Kidney Transplantation
Machine PerfusionIn the first meta-analysis examining the role of HMPO2 in kidney transplantation finds it may lower adverse events, particularly in DCD cases.

Who we are
Trusted, compassionate partners in the transplant technology space.
We deliver high-quality advanced transplantation technologies to support transplant teams all around the world. Decades of passion, research, and experience have forged the reputation of our products.