RM3 Kidney Perfusion system
Designed to control perfusion of either one or two explanted kidneys while it monitors perfusate flow, temperature, pressure, and renal resistance, the system continually circulates a cooled solution through the vascular vessels of the organs. The solution removes cell fragments and enables unbroken delivery of oxygen and substrates to the organs. The ion-pump activity as well as the metabolism, including adenosine triphosphate (ATP) synthesis, are thereby maintained during the perfusion. The hypothermic conditions slow down the metabolism and then decrease the cellular degradation of the organs.
BETTER OUTCOMES COMPARED TO STATIC STORAGE
RM3 system not only allows kidneys to be preserved in optimal and safe conditions, but also significantly improves graft function when compared with cold static storage.
Our perfusion technology has been shown to be beneficial to marginal donor kidneys, leading to more favorable immediate graft function and delayed graft function compared to static cold storage. Immediate graft function is defined by serum creatinine falls of more than 20% in the first 24 hours post-transplant. Serum creatinine is an important indicator of renal health because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the kidneys. Delayed graft function is defined as the need for dialysis within 7 days of transplantation.
For All kidney Anatomies
The perfusate solution circulates through the vasculature of the organs. Kidneys are cannulated by the renal artery. Different types of (single use or reprocessing) cannula are available to suit all anatomies.