CELSIOR is a flushing and cold storage solution for Heart Preservation specially formulated with impermeants to reduce swelling during cold storage,  efficient buffering system to protect against graft acidosis, substrates to help the production of energy in anaerobic conditions, antioxidants with permanently reduced glutathione, histidine, lactobionate and mannitol.

Clear to slightly yellow, sterile, non-pyrogenic solution for hypothermic flushing and storage of hearts. The solution is slightly acidic (approximate pH 7.3 at 20°C), slightly hypertonic (approximate calculated osmolarity 320-360 mOsmol/L) with low viscosity (1.15 cSt), and has a high buffering capacity (acidic approximately 11 mmol, alkaline approximately 7 mmol).

Ready to use: no additives required, no filtering required

Available in 1 Liter bags

Two year shelf life

Manufactured according to cGMP, by an ISO 13485 and ISO 9001 certified company

Ingredient & Concentration

Mannitol 60.0 mmol/L
Lactobionic Acid 80.0 mmol/L
Glutamic Acid 20.0 mmol/L
Histidine 30.0 mmol/L
Calcium Chloride 0.25 mmol/L
Potassium Chloride 15.0 mmol/L
Magnesium Chloride 13.0 mmol/L
Sodium Hydroxide 100.0 mmol/L
Reduced Glutathione 3.0 mmol/L
Water for Injection (WFI) Up to 1 liter



Product Components and Accessories